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    • 专利摘要:
    PURPOSE: A cosmetic base comprising nephrite powder and a preparation method thereof are provided to keep skin soft and moist and to prevent formation of fine wrinkle and horny substance by activating a cell and stimulating blood circulation and metabolism. CONSTITUTION: A cosmetic base comprises from 5 wt% to 99 wt% of a nephrite powder on the basis of the cosmetic such as a lotion, powdered cosmetics, lipsticks, eye makeup, pack for face, shampoo and hair lacquer etc. The nephrite powder has 100-1000 mesh of particle size and semi quantitative analysis(%) for composition ratio of the nephrite powder is as follows: silicon 34, magnesium 10, calcium 4.9, iron 0.23, aluminium 0.16, copper 0.17, cobalt 0.046, manganese 0.14, tin 0.024, beryllium 0.00072, silver 0.0013, titanium 0.0038, nickel 0.0028, chromium 0.0030.
    公开号:KR20000054996A
    申请号:KR1019990003398
    申请日:1999-02-02
    公开日:2000-09-05
    发明作者:김준한
    申请人:김준한；대일광업 주식회사；
    IPC主号:
    专利说明:

    Cosmetics Containing Purgatory Powder And Manufacturing Method Of Them {Cosmetics Which Contains Nephrite Jade Powder And Process For Preparing Thereof}
    The present invention relates to cosmetics such as cosmetic lotion, powder cosmetics, yeonji, eye cosmetics, facial packs, shampoos, set lotions and hair lacquers containing nephrite powder, and methods of manufacturing the same Climbing granite stone with ability to remove (headache, insomnia, indigestion, hand and foot), to remove impurities from objects (heavy metals, etc.), to improve water quality, and to promote the growth of animals and plants. The present invention relates to a cosmetic using a fine jade powder having a fine structure of brown rice fiber, and a method of producing the same.
    It is well known that many cosmetics used for body beauty have been developed in the past, and in particular, in order to provide functionalities such as wrinkle removal or blemish removal to roots, certain substances, such as vitamins or aloe or herbal medicine, which contain a lot of vitamins Although cosmetics containing the same have been developed, the effect is not obtained very well.
    In order to improve this point, purgatory with excellent disease treatment is contained in the cosmetics. Generally, jade is roughly divided into jadeite and nephrite, and jadeite is a lead masonry mineral belonging to the pyroxene family. Soda is a monoclinic substance, hardness is a dense mass like crystal, light is black, cyan, green, transparent or translucent, and jade usually refers to jadeite. .
    Purgatory is an inosilicates monolithic whiskey mineral, divided into purgatory and serpentine superbasic purgates in high-quality surrogate rocks, and their quality is fine. It is known that the structure, that is, the degree of fineness of the hollow granite-positive stone sperm into fastenings and fibers, and the finer the fiber, the better the quality. The jadeite and purgatory are two different ores, which, like most gemstones, contain silicon and oxygen, as published in the German medical literature (KRAFF der KRISTALLE und der EDELSTEINE) by Mauda Palmer Die Verborgene. However, jadeite is formed of granular crystals, whereas jadeite is composed of countless crystals such as fibers and hair and fine aggregates. Especially, jadeite is beneficial to the human body, unlike the sodium and aluminum components of jadeite. Its three minerals, calcium, iron and magnesium, have recently been reported to have a major impact on the healing of illnesses caused by high blood pressure, diabetic circulatory disorders, heart disease and kidney disorders when worn with purgatory. "Die Magie der Ed" by Hedy Brusisu elsteine).
    On the other hand, in Dongbobogam, a classic of oriental medicine, if you put jade into Omiju and Jiyuju, it turns into water, and if you put it in Honjangsu, it's good to eat. When eaten in the same size as 大, the waste is discharged to the outside of the body, 1 oxol, 1 jijicho (地 楡 草), 1 bream (1 米), and 3 egret (白露) are mixed together and put in a copper bowl. If you build a temple, the oxol is converted into water, which is called oxal (玉液) and is called Shinseonokjang (신 仙 玉 장), and it is based on Sinnonboncho, Dangboncho, and Herbaceous trees. Even if you take jade as a powder to make it enlightenment, it not only has the effect of moistening the five intestines and completely discharging waste products in the body, but also removing the heat in the stomach, which is effective for the digestive system, and bronchial Asthma, fever and heartburn Good and thirst quenching, sesame-like blouse, makes the body lighter and longer to fly, lubricates the lungs, helps the vocal cords nourish, nourish the hair, nourish the hair and function of the intestines In addition, it is effective to relieve stressful neurological disorders.In addition, it is good to eat white jade powder when the muscles are tense and the rat flies. Rubbing and scarring are the main ingredients of purgatory has been known to exert an excellent effect on the human body with little side effects.
    However, despite the fact that purgatory is known to have an excellent medical effect on the human body as described above, it is used only as some personal decorative jewelry ornaments such as necklaces, rings, and bracelets due to its scarcity. In particular, processing of purgatory requires a lot of time, effort, and careful attention, and it is impossible to craft it unless it is a skilled person with long experience. Since it is expensive, there is almost no development as a general household goods using purgatory with economical burden. It is true. Therefore, research and development of various household goods or medical supplies and body beauty supplies for urgent use of purgatory is urgently required.
    Therefore, the present inventors have the characteristic that purgatory gives a beneficial effect to humans such as the ability to treat such diseases (headache, insomnia, indigestion, hand-to-hand, etc.), odor removal ability, the ability to remove impurities of the object (heavy metal removal, etc.) Taking note of the fact that the research and experiments have been completed, a certain amount of purgatory powder is added during the preparation of the cosmetics, followed by kneading to prepare by degassing, filtration and cooling to promote metabolism of the purgatory component and blood of the skin. The present invention provides a cosmetic and a method for producing the same containing a nephrite powder capable of imparting moisturizing and softening properties to skin, promoting keratin prevention and hair protection, and UV protection.
    Another object of the present invention is to provide a maximal utilization of the purgatory powder by using the purgatory powder treated with residues or wastes derived from mining or jewelry processing.
    1 is a crystal structure diagram of a purgatory powder which shows the purgatory powder used in the present invention by a scanning electron microscope (SEM),
    2 is a scanning electron microscope (SEM) photograph of the jade water untreated silk used in the present invention,
    3 is a scanning electron microscope (SEM) photograph of the jade water treated silk used in the present invention,
    Figure 4 is a graph showing the change in the test sphere (mouse) activity after drinking drinking water used in the present invention,
    5 is a graph showing the results of observing the change in the total volume of the culture medium of digitalis lantana (Digitalis lanata) cells growing in the growth medium,
    FIG. 6 is a graph showing changes in the volume of digitalis lantana (Digitalis lanata) cells,
    7 is a graph showing changes in the bio weight of cells,
    8 is a graph showing the change in dry weight of cells,
    9 is a graph showing the pH change of the digitalis lanna (Digitalis lanata) culture medium,
    10 is a graph showing the pH change of the production medium after the addition of purgatory powder,
    11 is a view showing the result of the state condition of the analyzer;
    12 is a diagram showing an output of an analysis result.
    In order to achieve the above object, the cosmetic containing the purgatory powder of the present invention is purgatory with respect to 100 parts by weight of all cosmetics such as cosmetic lotion, powder cosmetics, rouge, eye cosmetics, face pack, shampoo, set lotion, hair lacquer, etc. It is characterized by containing 5 to 99 parts by weight in minutes.
    The nephrite powder is preferably made to achieve a particle size of 100 to 1000 mesh in order to feel good.
    It is preferable that the jade powder is the one defined as butch δ 18 O as the hollowstone chalcopyrite in the high quality surrogate rock.
    The composition ratio of the nephrite powder used above is made as follows.
    <Semi QuanTitative Analysis (%)>
    Silicon 34
    Magnesium 10
    Calcium 4.9
    Iron 0.23
    Aluminum 0.16
    Copper 0.17
    Cobalt0.046
    Manganese0.14
    Annotation 0.024
    Beryllium0.00072
    Is 0.0013
    Titanium 0.0038
    Nickel 0.0028
    Chromium 0.0030
    Miscellaneous 0
    In addition, in order to achieve the above object, the preparation method of the cosmetics containing the purgatory powder of the present invention is cosmetics during the manufacture of cosmetics such as cosmetics, powder cosmetics, rouge, eye cosmetics, face pack, shampoo, set lotion, hair lacquer, etc. Purified powder with respect to 100 parts by weight of 5 to 99 parts by weight, characterized in that the degassing, filtration and cooling.
    It is preferable that the jadeite powder is also defined as butch δ 18 O as a hollowstone chalcopyrite in high quality surrogate rock.
    In general, the particle size of the nephrite powder used in the present invention is preferably 100-350 mesh. However, when the ductility should be increased, it is advantageous to use the finer particles of 350-1000 mesh, which are finer particles. If the grain size of the jade powder is smaller than the above range, the roughness of the product is increased, which is not preferable.
    In addition, if the addition amount of jadeite powder is less than 5 parts by weight, it is not preferable because the effect due to the addition of jadeite is not preferable. In addition to reducing the properties, in particular ductility of the product to be vulnerable, due to the high price of the purgatory powder, the price of the product is increased, 99 parts by weight or less of the total weight of the cosmetic is preferred.
    The lotion is an emollient lotion (moisture lotion, milky lotion, narising lotion, narising milk, skin moisturizer, moisturizing emulsion, etc.) that gives skin moisturizing and flexibility, and gives blood promotion and flexibility of the skin. Massage lotion, cleansing lotion for cleansing and removing makeup, sun protection (protect emulsion, UV care milk, etc.) to block living UV rays, keratin softening, elbow lotion to soften dead skin, and protect hair Hair milk, hand lotion and body lotion for body hands.
    The purgatory powder is non-toxic and non-irritating to the human body. Due to these characteristics, nephrite powder is used in any cosmetics, but among them, cosmetic lotion, powder cosmetics, rouge, eye cosmetics, face pack, shampoo, set lotion and hair lacquer, etc. Is used. In other words, nephrite powder is used in cosmetic lotion by solution stability, non-toxicity and transparency, and it is used as a component of powder cosmetics (including solid cosmetics) by adsorption and coating power, and it is odorless, tasteless, non-toxic and highly water-soluble. It can be used as a non-toxic and non-irritating ingredient for eye liner which is an eye cosmetic, and it can be used as a component of facial packs for women with tension on the skin, and as a component of shampoo for health promotion effect. It is also used as an ingredient in cream toothpaste due to its high stability.
    In preparing the cosmetics according to the present invention, the nephrite powder can be freely used without any particular limitation in combination with other high polymers, low molecular weight compounds, inorganic compounds, flavoring agents, preservatives, etc. used in the manufacture of cosmetics, It is also used in cosmetics of any composition. As for the manufacture of cosmetics and the materials used in the manufacture, there are many examples, literatures and reports, such as cosmetics published by Namsan-dang and new cosmetics published by Fairytale Technology. You can refer to it.
    For example, for example, a lotion may be prepared by dissolving an aqueous phase (purified water, humectant, chelate, alkali, colorant, etc.) at a predetermined temperature (approximately 60 to 70 ° C), and an oil phase (oil-containing fatty acid, surfactant, drug). , Ultraviolet absorbent, preservative, fragrance, etc.) are heated and dissolved at a predetermined temperature (70-75 ° C.), and then preliminarily emulsified by adding to an aqueous phase. Pre-adjusted purgative powder was added thereto, stirred and mixed (approximately 60 to 70 DEG C), and then uniformly emulsified particles and nephrite powder by a powerful emulsifier (homomixer), followed by degassing and heat exchanger after filtration. It is cooled and commercialized. Other cosmetic preparations proceed similarly to the above.
    Hereinafter, the prescription example of the cosmetic containing the purgatory powder according to the present invention manufactured by the above method is as follows, but is not limited to these prescription examples.
    <Prescription Example 1>: Cosmetic Lotion
    Ethyl alcohol 10.0 parts (weight)
    Purgatory powder (350 to 1000 mesh) 5.0 parts
    Moisturizer (propylene glycol) 5.0 parts
    Olein alcohol 0.1 part
    1.2 parts of polyoxyl ethylene sorbitan fatty acid ester
    78.45 parts of purified water
    Antioxidant
    Preservative
    <Prescription example 2>: Set lotion
    Purgatory powder 30.0 parts (weight)
    Ethyl Alcohol 5.0 parts
    Glycerin 5.0 parts
    20.0 parts of purified water
    Sodium lauryl sulfonate3.0part
    0.01 part sugar
    Spices 2.0 parts
    Lubricant 2.0 parts
    Pigment amount
    <Prescription example 3>: Roll out
    Purgatory powder 10 parts (weight)
    80 parts of purified water
    Pectin part 2
    0.1 humectant
    Water-soluble pigment
    Spices
    Preservative
    <Prescription example 4>: Cosmetics around eyes
    Purgatory powder 5 parts (weight)
    Cetyl Alcohol2.0Part
    Sorbitan monooleate0.2part
    Propylene glycol6.0 part
    Ethyl alcohol 7.0 parts
    75.0 parts of purified water
    Preservative
    Pigment
    <Prescription Example 5> Coating agent of face
    Purity powder 20 parts (weight)
    Carboxymethyl Cellulose 5 parts
    Glycerin Part 2
    5 parts ethyl alcohol
    60 parts purified water
    Spices
    Preservative
    <Prescription example 6>: Shampoo
    Purgatory powder 10 parts (weight)
    13 parts of ethyl alcohol
    1.0 parts of polyoxy ethylene sorbitan monolaurate
    Glycerin 2.0part
    70 parts purified water
    Preservative
    Antioxidant Proper
    <Prescription Example 7>: Powder Cosmetic
    Purgatory powder 70.0 parts (weight)
    Zinc Part 4.5
    4.5 parts zinc stearate
    Pectin Part 11.0
    Spices
    Pigment amount
    <Prescription Example 8>: Powder Cosmetic
    Purgatory powder 75 parts (weight)
    Mineral oil part 8
    Cellulose derivatives 8 parts
    Purified water
    Spices
    Pigment amount
    The results of testing the effects of skin irritation and wrinkle removal on the products obtained from the above prescription examples were as follows.
    <Experimental example 1>: Skin irritation experiment
    50 adult men and women were attached to the upper soft skin of the upper arm and the cosmetics prepared according to the above example of the present invention after 12 hours to investigate the irritation of the skin, erythema, itching, allergies and the like. The results are shown in Table 1 below.
    Skin irritation% Of respondents No change in skin45 (90%) Slight itching after removal2 (4%) The attachment area is slightly red but disappears after 1-2 hours3 (6%) Significant irritation0 (0%)
    <Experimental example 2>: Wrinkle removal effect
    For 20 women after 30 years of age, clean the face after washing the face before bedtime, and after 1-3 minutes, make-up cosmetics prepared according to the above prescription only for wrinkles on the left eye Was applied to the morning and removed at the time of morning cleansing, compared with the right eye area (control). In addition, after the test period was over, the use of the product of the present invention was discontinued and the degree of disappearance of the effect was tested. The results are shown in Table 2 below.
    effect% Of respondents Significant wrinkle reduction or wrinkle disappearance4 (20%) Wrinkled depth becomes quite shallow12 (60%) Somewhat less wrinkles3 (15%) I'm not sure1 (5%)
    In addition, among the 19 respondents who saw the effect of wrinkle reduction and / or wrinkle removal after one month's use of the cosmetic according to the present invention, one week after the product was discontinued, the response of the product on the left eye was felt compared to the right eye. The number of Chinese characters was 17 (89%), demonstrating the sustainability of this product. As shown in Experimental Examples 1 and 2, the cosmetic of the present invention was not only excellent in the effect of reducing or removing wrinkles (95%), but also excellent in the persistence of the effect, and showed little irritation when attached to the skin. The following experimental examples were conducted on the efficacy of the purgatory powder contained in the cosmetic of the present invention and the effects of the purgatory powder on the living body, and the results are shown in the following tables.
    <Lead content test> sampleJade minutes Sample propertyWhite powder Job numberUnited States F.D.A.Affiliated Research Institute Federal IW 091394-1 WayAtomic absorption analysis resultNot detected
    <Heavy metal (Pb etc.)> sampleJade powder Sample propertyWhite Job numberFederal IW 080894-4 WayUSP 23 resultNot detected
    <Inorganic elution test> sampleJade powder Sample propertyWhite Job numberFederal IW 080894-4 WayAs resultAs
    100 g of the sample was extracted with 1 liter of water by autoclave treatment, and the extract liquid was analyzed.
    AnalyteResults (ppm)Detection limit (ppm) Arsenic (As)ND0.05 Barium (Ba)ND0.20 Cadmium (Cd)0.0070.005 Chlorine (Cl)NDOne Chrome (Cr)ND0.01 Copper (Cu)ND0.05 FeND0.10 PbND0.05 Manganese (Mn)ND0.02 Mercury (Hg)ND0.0005 Nitrate (NO3)ND0.1 Selenium (Se)ND0.05 Silver (Ag)ND0.01 Sulfate (SO4)2One Zinc (Zn)ND0.01
    (ND = concentration is below detection limit or not detected)
    As shown in the above experimental results, purgatory powder used in the present invention was proved to be safe when used in, for example, nipples for mammals, because no harmful lead, heavy metals, or other toxic components were detected.
    <Experiment 3>
    In this experiment, the effects of purgatory used in the present invention on the growth development and the quality of silkworms were examined (see FIGS. 1, 2 and 3).
    ① Materials and Methods
    1. Disclosed silkworm breed: Baekokjam
    2. Breeding time: November-December
    3. Breeding method: constant temperature and humidity, heraldic mulberry leaf meat
    4. Number of Disclosures: Control-150 Repeats 2 Repeats
    Treatment-130 Heads 2 Repeat
    5. Treatment details: Control-Mulberry feed by distilled water spray
    Treatment-Mulberry feed by spraying purgatory
    Processing Period: From 2nd Stage Sleep
    <Breeding results performed by fertilization treatment> divisionrepeatTreated Larva5th LarvaeTotal larvaeChrysalis percentage WorktimeWorktime%Indices ControlOne1507723791.3100 21507723776.6 Average1507723784.0 Treatment groupOne130715231574.185 2130715231568.2 Average130715231571.2
    divisionrepeatHigh yieldCocoon weightCocoon shell weightCocoon shell percentage (kg / 10,000)IndicesgIndicescgtime%Indices ControlOne17.91002.0810043.010020.7100 215.01.9639.019.9 Average16.52.0241.020.3 Treatment groupOne16.2932.1410644.010920.6102 214.62.1445.021.0 Average15.42.1444.520.8
    <Threading from Kochi by Oxygen Treatment> divisionCocoon filament length (m)Cocoon filament weight (cg)Silk size (d)Specific cutting length (m)Specific Cutting Filament Weight (cg)Thread Pulling Ability (%) Control1,22233.72.483.4723.469 Treatment group1,28336.32.551,00528.578
    divisionPercentage of unprocessed silk (%)Refinement (score)Adhesion (g / d)Elongation (%)Raw silk weight (kg) Control19.68953.803.472.75 Treatment group16.96963.931,0052.61
    <Changes in Larva Weight Due to Jade Treatment> divisionWeight of larvae immediately away from the third sloughWeight of larvae immediately away from the fourth slough5 weights on the 3rd dayMature caterpillars Control0.461.8520.8047.4 Treatment group0.471.9423.0352.2
    <Reduction effect of blood glucose by jade solution> Silkworm extractBlood sugarReduction effect of blood glucose Injection with maltose '(A)Injection into silkworm extract (B)Reduction amount (C = A-B) efficiency Water treatmentmg / 100mlmg / mlmg / ml% 64.0 ± 1.8727.7 ± 1.7036.3 56.7 Treated with jade solution69.6 ± 1.6220.7 ± 1.6248.9 70.3
    ': Injection of Silkworm Extract Previous
    result
    The weight of larvae was heavier than the control of distilled water in the age of messenger, especially 0.48 g / kg.
    2. The rate of fire was 71.2%, which was 15% lower than that of control, and 15.4g of 10,000 head was 7% lower than control.
    3. The total weight of the necrosis was 2.14 g, 6% heavier than the control, and 44.5 g, 9% heavier. The silk ratio was 2% higher than the control.
    4. Purgatory feeding showed better overall performance than control. In particular, the length of silk thread was long, the amount of silk was high, and the rate of hatchery was much higher than that of the control by about 9%.
    5. In the sands, the nephrophylls showed slightly thicker fine grains, and showed higher ratios of strength, elongation, and yield than those of the control.
    6. There was no significant difference in silk surface structure between control and treatment.
    7. The crystal structure of the nephrite nephrite had a pointed rod structure.
    <Experiment 4>
    In this experiment, we observed changes in the activity of mice drinking jade flour drinking water added with jade jade used in the present invention. As shown in FIG. 4, the mice in the positive control group began to stabilize the central nerve from 5 minutes after drinking Ubabitto (Note: Chinese name) in the stabilization experiment, and gradually returned to normal after 30 minutes. Mice in the control group showed ups and downs in activity rates and declined overall. The activity rate of the drinking test group (mouse) of the drinking water of jade powder was similar to that of the normal control group, but the average value of the overall activity rate was not only higher than that of the control group but also significantly different from that of the control group. .
    <Experiment 5>
    In this experimental example, infrared experiments were performed on purgatory powder.
    sampleJade minutes Sample propertyWhite method of inspectionPerkin elmer 137 resultAs
    <In IR spectrum>
    Form: Tetrahydrofran Liquefied Thin Film
    It appeared to match the pattern of polycarbonate resin and radiated electromagnetic waves with a wavelength of 6-52μ.
    <Experiment 6>
    In this Experimental Example, the chemical and biological oxygen requirements for the purgatory powder sample used in the present invention were performed as shown in Table 12 and Table 13 below.
    sampleJade minutes Sample propertyWhite WayStandard method resultAs
    divisionWater (control)Jade addition 5-day BOD224 mg / l223 mg / l COD115 mg / l110 mg / l
    <Experiment 7>
    In this experimental example, the experiment on the effect of the purgatory powder used in the present invention for the experimental sphere (rabbit) was performed as shown in Table 14.
    <Primary eye irritation test> sampleJade minutes Sample propertyMilky powder WayAs resultAs
    Method: US Federal Register Vol 43.No 163-1978.8.22 p37359
    Experimental procedure: Place 0.1 ml of the extract on the inverted lower eyelid of one eye, and gently hold for 1 second before placing the upper and lower eyelids. The other eye is not treated and observed as a control example. The treated eyes of the six rabbits were left unwashed, and the eyes of the three rabbits were washed with running lukewarm water for one minute immediately after treatment. Prior to treatment with the sample, the eyes were examined in advance by fluorescence and only animals that did not show corneal damage were used for the test. Eye lesions were observed 24 hours, 48 hours, 72 hours, 7 days and 14 days after treatment. The results were shown in Table 15 below.
    <Lesion degree of eyes> rabbittimeCorneal OpacityCorneal areaIris PriceConjunctival rednessConjunctival ChemosisConjunctival secretion # 1 fine chuck24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 2 fine chuck24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 3 fine24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 4 fine24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 5 fine24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0)
    # 6 fine chuck24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 7wash24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 8wash24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0) # 9wash24H000000 48H000000 72H000000 7D000000 scoreCorneal (0)Iris (0)Conjunctiva (0)
    I. Cornea
    (A) Opacity-Density (area for detoxification)
    Normal-0
    Scattered Diffusion Zones-Details of the iris are clearly visible-1
    Translucent areas that are easily identified, slightly blurred details of the iris-2
    Milky white area, details of the iris are not visible, pupil size is almost indistinguishable
    Opaque, no iris visible-4
    (B) corneal area
    Normal-0
    Less than 1/4, but not 0-1
    More than 1/4, less than 1/2-2
    1/2 or more, 3/4 or less-3
    More than 3/4, less than total area-4
    Score is A × B × 5, total max = 80
    II. Iris
    (A) value
    Normal-0
    Folded above normal, hyperemia, swelling, pericorneal congestion (these symptoms appear in any size, alone or in combination), the iris still responds to light (slow response is pronounced)-1
    Not responding to light, bleeding, total destruction (one or both of these symptoms)-2
    Score is A × 5, maximum possible total = 10
    III. conjunctiva
    (A) red tide (only related to the conjunctiva of the eyelid)
    Normal-0
    Blood vessels are surely reddened above normal-1
    More diffuse, deeper magenta, individual vessels not easily distinguished-2
    Spread red like beef-2
    (B) chemosis
    No Snooze-0
    Random swelling phenomenon over normal (including eye blink membrane)-1
    Clearly swollen with partial inversion of the eyelids-2
    Eyelid half closed and swollen-3
    Eyelid half to full closed and swollen-4
    (C) secretion
    Normal-0
    Any phenomenon other than normal (not including small amounts observed at the tip of the inner eye of normal animals)-1
    Secretions only on the eyelids and eyebrows adjacent to the eyelids-2
    Significant area around the eyes-3
    Score (A + B + C) × 2, total max = 20
    CONCLUSIONS: This sample was determined to be free of eye irritation and, therefore, was found to be suitable for use in eye cosmetic products.
    <Primary skin irritation test> sampleJade minutes Sample propertyWhite powder WayAs resultAs
    Method: US Federal Register Vol. 43, No. 163
    CTFA (The Cosmetic, Toiletry and Fragrance Association, Washington, D.C.) Technical Guidelines
    Experimental procedure: Patch testing was performed on the skin of the white rabbit and the original skin. The hair was cut short at the back and sides. Two areas, about 10 cm away, were selected as patch locations. One area is made of 4 small epidermal incisions in the patch area to remove the skin (two of which are perpendicular to the other and are "tic-tac-toe"). The patch is attached using a thin rubber band and adhesive tape Samples are introduced in each part in an amount of 0.5 ml (g) under the patch The body of the animal is wrapped with a rubberized cloth for 24 hours of exposure. After the patch was removed, the reaction at each site was evaluated based on the scores described below (see Table 17).
    Evaluation of Skin Response
    Erythema and crust formation
    No erythema-0
    Very weak erythema (recognizable barely)-1
    Properly identified erythema-2
    Moderate to severe erythema-3
    Severe erythema (beat red) to slight crust formation (deep damage)-4
    Edema
    No edema-0
    Very mild edema (recognizable barely)-1
    Slight edema (it is obvious that the edges of the area are prominent)-2
    Moderate edema (approximately 1 mm up)-3
    rabbit24 hours72 hours Original skinWorn skinOriginal skinWorn skin EREDEREDEREDERED #One00000000 #200000000 # 300000000 #400000000 # 500000000 # 600000000
    Conclusions: This sample was determined to have no skin irritation. Therefore it appeared to be suitable for use in skin cosmetic products.
    <Acute oral toxicity [(0.5 g) / 100 g body weight] experiment> samplePurgatory powder Sample propertyWhite powder WayAs resultSame as Table 24 below
    ratgenderInitial weight (g)Dosage (ml)Lag weight (g)Toxicity OneF2071.0219none 2F2111.1226none 3F2151.1225none 4F2081.0217none 5F2001.0213none 6M2271.1235none 7M2161.1224none 8M2051.0218none 9M2101.1224none 10M2121.1221none
    Preparation of Samples: A portion of the sample was placed in sterile distilled water and boiled for 10 minutes to extract, and the extract was administered by intubation in an amount of 0.5 g per 100 g of body weight.
    CONCLUSIONS: The sample meets the criteria for no oral toxicity.
    <Experimental example 8>
    This experiment example is the process and results of the experiment performed by Inha University bioinformatics system engineering laboratory to investigate the various effects of purgatory powder used in the present invention on the living body. In this experiment, 70% of the constituent elements of the human body are water. Therefore, the impact of water on the water and the impact on the human body are investigated. Experiments on the effects were performed.
    A. Hard water change
    <Experiment 1>
    100 ml of artificially-made hard water was transferred to each of the four flasks by 50 ml, and purgatory was placed on the bottom of two flasks for about 10 minutes.
    To determine the change in hardness, a titration method using ethylene diamineacetic acid (hereinafter referred to as "EDTA" titer 2.9412) was used. 1 ml of a buffer solution of pH 10, EBT was used as an indicator.
    The change in hardness was measured by the amount of EDTA until the moment when the color of the hard water was changed by EDTA. At this time, the color returned to its original state over time, but in this experiment, the measurement was made based on the changing moment.
    <Result 1>
    At 100ppm of hard water, it takes 1.70ml of EDTA.
    It takes 1.25ml of EDTA after purgatory test, so the hardness of 100.00ppm is lowered to 73.53ppm. That is, the hardness of 100.00 ppm was softened 26.47%.
    <Experiment 2>
    200 ml of 100ppm hard water made in the same manner as in Experiment 1 was transferred to a beaker to immerse the purgatory. After about 30 minutes, the water in the beaker was divided into three flasks to measure the change in hardness. In this experiment, the hardness was measured by adding EDTA until the color of hard water did not change any more after the color of hard water changed by EDTA.
    <Result 2>
    Each 100ppm hard water before purgatory experiment
    89.62 ppm
    91.19ppm
    89.62 ppm
    Average 90.14ppm, thus 9.9% hardness decrease
    <Experiment 3>
    This experiment was conducted with tap water. Tap water was placed in a container and transferred to six flasks, and purgatory was placed at the bottom of three flasks, and hardness was measured after about 5 minutes.
    <Result 3>
    * Tap water without purgatory
    97.48 ppm
    97.48 ppm
    97.48 ppm
    Average 97.48 ppm
    * Tap water after purgatory experiment
    91.19ppm
    91.19ppm
    91.19ppm
    Average 91.19ppm therefore, hardness decrease of 6.5%
    I. Effect of Purgatory on the Proliferation of Digital Plant Suspensions of Digitalis lanata
    Effects of Purgatory on the Growth of Digitalis lanata Cells in Growth Medium
    FIG. 5 is a graph showing changes in culture medium volume of cells grown in growth medium for 11 days, and FIG. 6 is a graph showing changes in cell volume, in proportion to the increase of cells growing over time. As the depletion of and the evaporation of the medium occur, the volume change of the whole culture reflects these factors. In particular, humidity and temperature in the atmosphere are closely related to the evaporation of the medium, and such factors also affect the cell growth rate.
    As shown in the figure, the use of purgatory shows that the volume of the total culture solution is slightly decreased compared to the control group which is not used. This is because the use of purgatory rather than the control group has a faster cell growth rate against the evaporation of the medium or the depletion of nutrients, and thus, it is possible to offset the rapid decrease of the depleted medium to some extent. This phenomenon is observed in the case of continuous use of purgatory from day 4 to day 11 after inoculation of cells as shown in Fig. 6 measuring the volume change of the sunk cells only increase the volume of the cell than the unused control group. This fact can be estimated. Therefore, the use of nephrite showed a faster cell growth rate than the control without the nephrite. These results can be said to be the result of delaying the decrease of the total volume than the control by offsetting the decrease in the total culture volume due to nutrient depletion and medium evaporation. In addition, the result of comparing the volume of the increased cell alone is also observed to show a tendency to gradually increase the cell volume after 4 days, it is thought that can support this result.
    Cell proliferation and dry weight are the most common measures of cell proliferation. In general, the growth curve of all cells is represented by the S-shaped curve, which can be classified into four stages. Lag phase, which is a period of adaptation to the medium, in which there is no cell proliferation and no mass growth, and an exponential curve showing a steep slope due to a mass increase at a rapid proliferation rate after this period. phase), the stationary phase, which has a maximum growth to some extent, and the Chinese food is slowed down and shows no mass increase, and the cell ruptures due to the depletion of nutrients, the release of toxic components, and the saturation of cell density. It can be divided into a dead phase where the total cell volume or mass decreases due to the tendency to die.
    7 and 8 are the results of measuring the cell biomass and dry weight.
    7 follows the growth curve of these four stages. In the case of using jade, after 7 days, the growth rate was slightly higher than that of the control without jade, and the growth stopped until 10 days, unlike the control showing the decrease in cell biomass. have. This is remarkable in that cell growth is continued even when the concentration of nutrient is almost depleted and the concentration in the medium becomes zero compared with the change in the concentration of glucose, a nutrient that acts as the main metabolic substrate in the medium. It is common to show a tendency to stop the growth and decrease the growth rate at the point of depletion of the influenced ingredients, like the control without purgatory, but the effect of purgatory on cell growth is different from purgatory It is assumed that there is. This result is also shown in Figure 8 shows the cell growth proliferating at a higher rate than the control after 3 days, and from 9 days after, the same phenomenon as in FIG. As a result, cells grown near nephrite in the growth medium showed better effect on cell growth than the control group that did not. Digitalis lanata plant cells, which have a growth limit of about 10 days, are maintained in a stable state that does not cause necrosis of cells without exchanging with new medium even after 10 days when cultured with purgatory. Rather, it is expected that cell proliferation may be an advantageous method for optimizing cell growth and concentration in the production process for the production of useful substances.
    ② Effect of Purgatory on Changes in Medium pH
    9 is a graph showing the pH change in the cell growth medium, Figure 10 is a graph showing the pH change of the production medium after the addition of purgatory powder.
    Figure 9 is a measure of the change in the pH of the medium in the control medium with and without the purgatory in the growth medium. The control group shows a general tendency of pH in the medium applied to the plant cells, which gradually decreases over time and is maintained at a certain level. However, when using purgatory, it showed a similar pattern to the control group until day 7, and gradually increased. This phenomenon is extreme in the result of FIG. . The control group without added jade powder showed a consistent drop in pH, while the addition of jade powder showed a tendency to maintain the value to some extent. It is assumed that it acts as a cause.
    ③ Results of analysis of water quality for purgatory
    FIG. 11 is a view showing the condition of the water analyzer containing the purgatory powder used in the present invention, and FIG.
    The data from FIG. 11 and FIG. 12 are summarized in Table 20 to Table 23. Table 20 shows each analysis item for sample 1 after a lapse of 48 hours with 20 g of nephrite lump in solution. In Table 20, there is little change in each measurement item, and the effect of purgatory is hardly seen.
    Table 21 shows the measurement values for each analysis item in Sample 2 after 48 hours of placing 20g of jade purgatory blocks outside of the solution.
    Table 23 also shows the measured values for each analysis item in Sample 4 after 48 hours of purifying powder outside the solution. However, in case of Sample 3, the data measured for each analysis item of the sample 48 hours elapsed after 20 g of purgatory powder was added to the solution is shown in Table 22. This change is as follows.
    Cr, Pb, Ni, and Co, which are harmful to the human body, changed significantly after 48 hours. Cr was removed in the absence of purgatory powder, that is, 45.30 mg before the reaction was removed to 0 after 48 hours in the purifying powder, and Pb was also completely removed from 13.76 mg to zero. Ni decreased from 51.8 mg to 1.733 mg and Co also decreased from 52.69 mg to 11.94 mg. Mg, one of the necessary elements in the human body, increased from 48.36mg to 55.74mg.
    The hydrogen ion concentration of distilled water was acidic at pH 3.5, but after the reaction, it became neutral at pH 6.8, and the conductivity was also rapidly decreased. to be.
    Analytical results before and after the reaction in solution Purgatory lumps (purg of jade in solution) (Sample 1): Purgatory lumps in solution (20 g) ItemBefore the reactionAfter reaction (48hr)Change pH3.53.82- Ni51.8 mg51.75mg- Co52.69mg52.54mg- Cr45.30mg43.88mg- Mg48.36mg48.59 mg- Pb13.76 mg13.90mg-
    Results of analysis of purgatory lumps outside the solution. (Sample 2): lump of purgatory jade (20g) ItemBefore the reactionAfter reaction (48hr)Change pH3.53.65- Ni51.8 mg48.92mg- Co52.69mg49.83mg- Cr45.30mg41.23mg- Mg48.36mg47.97mg- Pb13.76 mg15.1mg-
    Analysis result when adding purgatory powder to solution. (Sample 3): Purgatory powder in solution (20g) ItemBefore the reactionAfter reaction (48hr)Change pH3.56.8+3.3 Ni51.8 mg1.733 mg-50.06mg Co52.69mg11.94mg-40.75mg Cr45.30mg0mg-45.30mg Mg48.36mg55.74mg+ 7.38mg Pb13.76 mg0mg-13.76 mg
    Analysis result when purgatory powder was placed outside solution (Sample 4): Purgatory powder outside solution (20g) ItemBefore the reactionAfter reaction (48hr)Change pH3.53.7- Ni51.8 mg51.53 mg- Co52.69mg52.55mg- Cr45.30mg43.0mg- Mg48.36mg48.39mg- Pb13.76 mg14.29 g-
    As described above, in the case of Digitalis lanata plant suspension cells cultured for one week with nephrite close, proliferation of more than about 30% was observed. This is a rare proliferative result even in the various experiments performed for the proliferation effect on conventional Digigitalis lanata plant cells for high concentration culture. In addition, experiments on how purgatory water affects hard water showed that soft water softened hard water without contact with water. Particularly, in the component analysis experiments on water using distilled water, precipitation of nephrite was carried out. After 48 hours, in the component analysis, the pH was increased, the Ni and Co components were reduced, the Cr and Pb were removed, and the heavy metals were removed. An unusual phenomenon was observed that led to the phenomenon of.
    As such, purgatory powder according to the present invention has not yet been clearly identified theoretically, but also changes the hardness of water without contact with water, and also proliferates more than 30% of the digitalis lanna plant (Digitalis lanata) plant suspension cells, The elimination of heavy metals harmful to the human body, such as the reduction of Ni and Co components, and the removal of Cr and Pb, is believed to be due to the radiation effect of the electromagnetic wave wavelengths of the purgatory powder and the ionic reaction by the mineral components contained in the nephrite. These facts will be proved by the efficacy shown in the above-described products of the present invention, and the experimental results are particularly effective on human skin health due to the properties of purgatory powder and the effect of purgatory when using cosmetics containing the purgatory powder of the present invention. It will prove to be a useful effect.
    As described above, according to the present invention, by adding a nephrite powder to make cosmetics, when using the product made using the components produced from the purgatory is excellent medical, such as cell function activation, blood circulation and metabolism promotion It has the function of protecting skin's flexibility, moisture, exfoliation, UV protection, wrinkle prevention and hair protection.
    权利要求:
    Claims (6)
    [1" claim-type="Currently amended] Containing nephrite powder containing 5 to 99 parts by weight of nephrite powder with respect to 100 parts by weight of all cosmetics such as cosmetic lotion, powder cosmetics, rouge, eye cosmetics, face pack, shampoo, set lotion and hair lacquer Cosmetics.
    [2" claim-type="Currently amended] According to claim 1, wherein the nephrite powder is a cosmetic containing a nephrite powder, characterized in that the particle size of 100 to 1000 mesh.
    [3" claim-type="Currently amended] The cosmetic product containing jadeite powder according to claim 1, wherein the jadeite powder is defined as butch δ 18 O as a hollowstone jadeite in high-quality surrogate rock.
    [4" claim-type="Currently amended] The cosmetic composition according to any one of claims 1 to 3, wherein the composition ratio of the purgatory powder used in the above is made as follows.
    <Semi QuanTitative Analysis (%)>
    Silicon 34
    Magnesium 10
    Calcium 4.9
    Iron 0.23
    Aluminum 0.16
    Copper 0.17
    Cobalt0.046
    Manganese 0.14
    Tin 0.024
    Beryllium0.00072
    Is 0.0013
    Titanium 0.0038
    Nickel 0.0028
    Chromium 0.0030
    Miscellaneous 0
    [5" claim-type="Currently amended] Purified powder is contained in an amount of 5 to 99 parts by weight based on 100 parts by weight of cosmetics such as cosmetic lotion, powder cosmetics, rouge, eye cosmetics, face pack, shampoo, set lotion and hair lacquer. Method for producing a cosmetic containing a purgatory powder, characterized in that.
    [6" claim-type="Currently amended] The method of claim 1, wherein the nephrite powder is defined as butch δ18 O as a hollowstone in the high quality surrogate rock.
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    同族专利:
    公开号 | 公开日
    KR100279694B1|2001-01-15|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    法律状态:
    1999-02-02|Application filed by 김준한, 대일광업 주식회사
    1999-02-02|Priority to KR1019990003398A
    2000-09-05|Publication of KR20000054996A
    2001-01-15|Application granted
    2001-01-15|Publication of KR100279694B1
    优先权:
    申请号 | 申请日 | 专利标题
    KR1019990003398A|KR100279694B1|1999-02-02|1999-02-02|Cosmetics Which Contains Nephrite Jade Powder And Process For Preparing Thereof|
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